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Pharmaceutical utility systems — water purification and distribution infrastructure

Utilities in Pharmaceutical Production

PHARMA TECHNOLOGY

In pharmaceutical manufacturing, utility quality is not a support function — it is a critical process parameter. Purified water, water for injection, compressed air and pure steam must meet the strict specifications of international pharmacopoeias (EP, USP, JP) and GMP regulations at every point of use.

Klarwin designs, implements and validates complete utility systems — from feed water pre-treatment through production, distribution and storage, to real-time monitoring of critical parameters across distribution loops.

Pharmaceutical compressed air filtration and clean room HVAC systems

Air — Filtration and Control for Pharmaceutical Environments

Air quality in pharmaceutical manufacturing is a controlled parameter, not a variable. Airborne particles, microorganisms and chemical contaminants can compromise batch integrity and trigger costly non-conformances.

Klarwin integrates two complementary systems:

  • Compressed air filtration (Cytiva) — submicron particle removal, oil aerosol separation, sterile filtration validated to GMP, with stainless steel construction rated for SIP and autoclave cycles
  • HVAC filtration for cleanrooms (AAF) — HEPA/ULPA solutions up to class U17, with integral efficiency at MPPS of up to 99.999995%, compatible with H₂O₂ decontamination and in-situ DOP/PAO integrity testing

Water — Purified Water and Water for Injection Systems

Water is the most used raw material in pharmaceutical production. Every drop of Purified Water (PW) or Water for Injection (WFI) must meet pharmacopoeia specifications (EP, USP, JP) — from production through distribution to point of use.

Klarwin designs complete pharmaceutical water systems integrating:

Pre-treatment — mechanical filtration, activated carbon, softening, microfiltration
PW production — reverse osmosis (RO), electrodeionization (EDI), ultrafiltration (UF), UV disinfection
WFI production — multi-effect distillation (MED), mechanical vapor compression (VC), or cold WFI (RO+EDI+UF+ozone/UV)
Distribution & storage — 316L electropolished stainless steel recirculation loops, sanitary tanks with CIP, real-time monitoring of conductivity, TOC and temperature
Pharmaceutical water purification system — PW and WFI production and distribution
TECNinox clean and pure steam generator for pharmaceutical sterilization

Clean and Pure Steam — TECNinox Generators

Steam quality directly influences the safety of sterilization processes and finished product integrity. Klarwin integrates TECNinox generators — built entirely in 316L stainless steel with sanitary finish (Ra ≤ 0.4 µm), compliant with EP and USP.

  • Clean steam — from purified water (PW), for indirect heating applications
  • Pure steam — from water for injection (WFI), for direct product/surface contact
  • Precise pressure and temperature control, automatic non-condensable gas evacuation, continuous conductivity monitoring
BACK TO PHARMA TECHNOLOGY

We engineer the pharma utilities of your plant

From compressed air to WFI water and pure steam — Klarwin designs, delivers and commissions the critical utility systems. Talk to an engineer who understands GMP requirements.

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